A former DJ for MTV Australia, she is a model and recording artist. In late 2012, she released her debut single "Guilty Pleasure." In 2010, she debuted her fashion business, Milk and Honey Designed by Ruby Rose. In 2019, she was cast in the CW's Batwoman as the titular character.
She rose to notoriety after coming in second place in the Girlfriend Magazine Model Search in 2002.
She started a YouTube account in late 2010 and has about 27,000 subscribers and over 2,000,000 unique views by early 2015.
Katia Langenheim, her mother, reared her as a single mom. Ruby Rose, an out lesbian, married fellow Australian model Catherine McNeil in 2010. She later married Phoebe Dahl in early 2014, however the couple divorced in December 2015. In 2016, she began dating musician Jessica Origliasso, with whom she dated until mid-2018.