Malignancy is the tendency of a medical condition to become progressively worse. Malignancy is most familiar as a characterization of cancer. A malignant tumor contrasts with a non-cancerous benign tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues, and may be capable of spreading to distant tissues. A benign tumor has none of those properties. Malignancy in cancers is characterized by anaplasia, invasiveness, and metastasis. Malignant tumors are also characterized by genome instability, so that cancers, as assessed by whole genome sequencing, frequently have between 10,000 and 100,000 mutations in their entire genomes. Cancers usually show tumour heterogeneity, containing multiple subclones. They also frequently have reduced expression of DNA repair enzymes due to epigenetic methylation of DNA repair genes or altered microRNAs that control DNA repair gene expression.
| Specialty | Oncology |
| Symptoms | Fatigue, lump(s), change in skin, abnormal bleeding, prolonged cough, unexplained weight loss |
| Risk factors | Smoking, sun exposure, genetics - history of malignancy, solid organ transplantation (post-transplant malignancy), infectious diseases |
| Diagnostic method | Biposy |
| Treatment | Photoradiation therapy, surgery, chemotherapy, hyperthermia |
| Frequency | 442.4 per 100,000 per year |
| Deaths | ~10 million per year |
About Malignant
A woman is paralyzed by fear from a series of shocking visions. Her torment becomes more intense when she discovers that her visions are becoming a terrible reality. The film was directed by James Wan.
Achievement of Malignant
Filming took place in Los Angeles between September and December of 2019.
Top Facts You Did Not Know About Malignant
Precancerous condition - A precancerous condition is a condition or lesion involving abnormal cells which are associated with an increased risk of developing into cancer. Clinically, precancerous conditions encompass a variety of conditions or lesions with an increased risk of developing into cancer.. Oncology.. Medical terminology.
Latest information about Malignant updated on September 18 2021.
